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Preparation and Characterization of Membrane Oxygenator- Oriented Polysulfone Asymmetric Membranes

Authors： Lv Quan1, Yin Hai-yan 1, Yu Wen-kui 2, Huang Xin 1, Li Lei 1*

Units： 1.Department of Chemical Engineering, College of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, P.R.China; 2. Medical School, Nanjing University, Nanjing 210093, P.R.China

KeyWords： PSf membrane oxygenator; permeation flux; CWPPM; transport rate

ClassificationCode：TB324

year,volume(issue):pagination： 2013, 33(5):25-29

Abstract：

Membrane oxygenator-oriented polysulfone(PSF) asymmetric membranes were prepared by wet phase inversion method and their performance was characterized primarily. It was demonstrated through experiments of membranes preparation that with increasing PSF concentration of casting solution, permeation flux of O2 and CO2 decreased and critical water permeability pressure of membrane（CWPPM） increased. Moreover, prolonging pre-volatilization time of wet membranes had a disadvantage on gas permeation but had little effect on CWPPM. Accordingly, the optimal PSF concentration of casting solution and pre-volatilization time of wet membranes is 15% and 5s, respectively. Besides, application experimental results of gas-liquid transport through PSF membrane oxygenator indicated that when the flow rate of bovine blood reached 1.5L/min, permeation flux of O2 and CO2 were 163ml/min and 148ml/min, respectively, which could achieve the gas exchange transmission capacity of membrane oxygenator.

Funds：

江苏省自然科学基金面上项目（BK2012727）

AuthorIntro：

吕权（1987—），男，河南省信阳市人，硕士研究生，研究方向为人工肺用膜材料；李磊，男，副教授，通讯联系人，电话: ( 025 ) 83596665- 810, E-mail：ll-nju@163.com.

Reference：

[1]M.W.Lim.The history of extracorporeal oxygenator [J] . Anaesthesia, 2006, 61, 984–995
[2] Brittany A Zwischenberger, Lindsey A Clemson and Joseph B Zwischenberger. Artificial lung: progress and prototypes[J]. Expert Rev. Med. Devices2006, 3(4): 485-498.
[3] Eisuke Tatsumi. Arti?cial lungs: current state and trends of clinical use and research and development [J]. J Artif Organs , 2007,10:1–5.
[4]Frank wiese. Membrane for artificial lung[M]. Membrane for the life sciences: 49-68.
[5]Don N. Gray. Polymeric membrane for artificial lung [M]. American chemical society: Washington DC,1984, 150-161.
[6] Hiroyoshi Kawakami. Polymeric membrane materials for artificial organs[J].Artif Orgasns (2008) 11:177-182
[7]Tadashi Motomura, Tomohiro Maeda. Development of silicone rubber hollow fiber membrane oxygenator for ECMO. Artificial Organs 27(11):1050–1056
[8] Mário DRUMMOND, Domingo M.BRAILE Technological evolution of membrane oxygenators[J] Braz J Cardiovasc Surg 2005; 20(4): 432-437.
[9] 杨瑜静,谷雪莲,徐秀林等. 复用血液透析器(人工肾)膜表面粘附蛋白的实验研究[J].膜科学与技术.2008,28(6):79-83.
[10] Dongliang Wang, W.K. Teo, K.Li. Preparation and characterization of high-?ux polysulfone hollow ?bre gas separation membranes[J]. Journal of Membrane Science , 2002, 204,247–256.
[11] Robles NR, Murga L, Galvan S, Esparrago JF,
Sanchez-Casado E. Hemodialysis with cuprophane or polysulfone: effects on uremic polyneuropathy [J]. American Jouranal of disease, 1993, 21(3):282-287.
[12] Fawen Wu, Lei Li, Zhihong Xu. Transport study of pure and mixed gases through PDMS membrane[J]. Chemical Engineering Journal 2006,11,751–59.
[13] P.S.T. Machado, A.C. Habert, C.P. Borges. Membrane formation mechanism based on precipitation kinetics and membrane morphology [J]. Journal of Membrane Science 1999, 155, 171-183.
[14] Motohiro Niwa, Hiroyoshi Kawakami, Shoji Nagaoka. Development of a Novel Polyimide Hollow-?ber Oxygenator[J]. Arti?cial Organs 28(5): 487–495
[15] William J. Federspiel Kristie A. Henchir. Lung, Artificial: Basic Principles and Current Applications [M].University of Pittsbrugh, Pennsylvania, U.S.A, 909-921
[16] C Visser and DS de Jong. Clinical evaluation of six hollow-fibre membrane oxygenators. University Hospital Maastricht, perfusion, 1997, 12,357-368.

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