| 多巴胺的自聚-附着行为与膜表面功能化 |
| 作者: 浙江大学 高分子科学与工程学系,高分子合成与功能构造教育部重点实验室, |
| 单位: 浙江大学 高分子科学与工程学系,高分子合成与功能构造教育部重点实验室, |
| 关键词: 多巴胺;多巴;儿茶酚衍生物;功能化;仿生;表面改性 |
| DOI号: |
| 分类号: TQQ028.8 |
| 出版年,卷(期):页码: 2011, 31(3):32-38 |
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摘要: |
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多巴胺(dopamine)是一种生物神经递质,在水溶液条件下,它能在溶解氧的作用下发生氧化-交联反应,形成强力附着于固体材料表面的聚多巴胺复合薄层。基于多巴胺的这一特性,近年来膜技术研究者们通过多巴胺在固体基膜上的自聚-复合,对膜进行表面改性,并以具有反应活性的聚多巴胺复合层为平台,对膜进行进一步的表面修饰,实现膜的功能化。本文论述了多巴胺在膜表面修饰与功能化方面的研究进展,应用领域包括超/微滤膜、生物医用膜以及渗透汽化膜等。 |
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Dopamine is a kind of biological neurotransmitter. In aqueous solution, it can be oxidized by dissolved oxygen and undergoes an oxidation-crosslinking reaction, forming a composite layer of polydopamine that strongly attaches to a substrate. Based on the characteristics of dopamine, in recent years, membrane technology researchers have performed surface modification via the self-polymerization-composite of dopamine on solid basement-membranes. Besides, the polydopamine composite layer with high reactivity offers a platform for further surface modification and functionalization. In this paper, research progress on modification and functionalization of membrane surface using dopamine was reviewed, the application fields included ultra/micro filtration, biomedical membranes and pervaporation film, etc. |
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基金项目: |
| 国家“973”计划项目(2009CB623402),国家自然科学基金项目(50803054),浙江省自然科学基金项目(Y4100204)资助 |
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作者简介: |
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Dopamine is a kind of biological neurotransmitter. In aqueous solution, it can be oxidized by dissolved oxygen and undergoes an oxidation-crosslinking reaction, forming a composite layer of polydopamine that strongly attaches to a substrate. Based on the characteristics of dopamine, in recent years, membrane technology researchers have performed surface modification via the self-polymerization-composite of dopamine on solid basement-membranes. Besides, the polydopamine composite layer with high reactivity offers a platform for further surface modification and functionalization. In this paper, research progress on modification and functionalization of membrane surface using dopamine was reviewed, the application fields included ultra/micro filtration, biomedical membranes and pervaporation film, etc. |
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参考文献: |
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[1] Lee H, Scherer NF, Messersmith PB. Single-molecule mechanics of mussel adhesion [J]. P Natl Acad Sci USA, 2006, 103: 12999-13003. |
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