| 亚临界通量操作对黄连解毒汤超滤过程的影响 |
| 作者: 南京中医药大学 中药复方分离工程重点实验室,江苏 南京210029 |
| 单位: 南京中医药大学 中药复方分离工程重点实验室,江苏 南京210029 |
| 关键词: 中药水提液;超滤;亚临界通量 |
| DOI号: |
| 分类号: TQ028.8 |
| 出版年,卷(期):页码: 2013, 33(3):81-87 |
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摘要: |
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将临界通量概念引入中药水提液复杂体系,以中药复方黄连解毒汤水提液为实验对象,通过测定中空纤维膜超滤过程的临界通量,考察了亚临界通量操作下的膜系统运行状态。结果表明,在错流流速0.15 m/s,压力0.04 MPa的亚临界通量操作下,膜稳定通量与初始通量相比降低了5.5%;而在0.07 MPa和0.10 MPa的超临界通量操作下,其值分别为32.1%、42.2%。相对稳定膜污染阻力在0.04 MPa 、0.07 MPa和0.10 MPa条件下分别为3.0、7.5和15.8。亚临界通量操作对于优化操作条件,有效降低膜污染,节约生产成本,指导中药水提液膜过滤精制的实际生产应用有着重要的意义。 |
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The concept of critical flux is introduced into the complex system of Chinese herb extractions.The critical flux of the traditional Chinese medicine compound Huanglian jiedu decoction is determined in the hollow fiber membrane ultrafiltration process and the sub-critical flux operation status is studied.The results show that under the sub-critical flux operation when the pressure is 0.04 MPa and the cross-flux equals 0.15 m/s,the stable permeate flux is only reduced by 5.5 % compared to the initial flux.However, under the ultra-critical flux operation when the pressure is 0.07 MPa and 0.10 MPa,the values are 32.1 % and 42.2 % respectively.The relative stability fouling resistance under the pressure of 0.04 MPa、0.07 MPa and 0.10 MPa is 3.0、7.5 and 15.8 respectively.Sub-critical flux operation of great significance to optimize the operating conditions to reduce membrane fouling ,saving production costs ,and guide the actual refining production process of Chinese herb extractions using membrane filtration technology. |
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基金项目: |
| 国家自然科学基金(30572374,30873449,30973950);中药制药过程新技术国家重点实验室开放基金资助(SKL2010Z0101) |
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作者简介: |
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The concept of critical flux is introduced into the complex system of Chinese herb extractions.The critical flux of the traditional Chinese medicine compound Huanglian jiedu decoction is determined in the hollow fiber membrane ultrafiltration process and the sub-critical flux operation status is studied.The results show that under the sub-critical flux operation when the pressure is 0.04 MPa and the cross-flux equals 0.15 m/s,the stable permeate flux is only reduced by 5.5 % compared to the initial flux.However, under the ultra-critical flux operation when the pressure is 0.07 MPa and 0.10 MPa,the values are 32.1 % and 42.2 % respectively.The relative stability fouling resistance under the pressure of 0.04 MPa、0.07 MPa and 0.10 MPa is 3.0、7.5 and 15.8 respectively.Sub-critical flux operation of great significance to optimize the operating conditions to reduce membrane fouling ,saving production costs ,and guide the actual refining production process of Chinese herb extractions using membrane filtration technology. |
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参考文献: |
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[1]董 强,刘立敏,林淑钦,等.中药复方水提液澄清过程中陶瓷膜污染的防治研究[J].膜科学与技术,2004,24(6):34-37. |
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