| 聚偏氟乙烯中空纤维医用膜的研制初探 |
| 作者: 中空纤维膜材料与膜过程国家重点实验室,生物化工研究所, |
| 单位: 中空纤维膜材料与膜过程国家重点实验室,生物化工研究所, |
| 关键词: PVDF;血液透析膜;膜性能;非溶剂相转化法 |
| DOI号: |
| 分类号: TQ028.8, R318.08 |
| 出版年,卷(期):页码: 2013, 33(4):23-27 |
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摘要: |
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本文利用非溶剂相转化法,制备不同聚偏氟乙烯(PVDF)改性膜。研究了PVDF与聚乙二醇(PEG)- 400固含量对膜性能的影响,并将PVDF改性膜与市售血液透析膜F60S的性能进行了对比分析。结果表明,随着PVDF固含量的增加,膜分离孔径和纯水通量逐渐减小,BSA截留率和机械性能提高;随着PEG-400固含量的增加,膜分离孔径先减小后增大,BSA截留率先增加后减小,纯水通量逐渐提高,机械性能下降。PVDF/PEG膜分离孔径与纯水通量比F60S膜略低,BSA截留率、机械性能、血液相容性与F60S膜相比均具优势。 |
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In this present study, different PVDF modified membranes were prepared by non-solvent induced phase separation (NIPS) method. The effects of PVDF solid content, polyethylene glycol (PEG) - 400 solid content on membranes performances were researched. In addition, the performance of different PVDF modified membranes and F60S membranes, saled on the market, were compared and analysed. The results showed that, the membranes aperture and pure water flux decreases gradually with the increase of PVDF solid content, BSA retention rate and mechanical property increased. The aperture of membranes decreased and then increased with PEG-400 solid content increased, BSA retention rate increased and then decreased gradually, the pure water flux increased, and mechanical properties decreased. The aperture and pure water flux of PVDF/PEG membrane were slightly smaller than F60S membrane, BSA retention rate, mechanical properties and blood compatibility of PVDF/PEG membrane were better than F60S membrane. |
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基金项目: |
| 国家自然科学基金项目(21176188,21106100);高等学校博士学科点专项科研基金(20111201110004);天津市应用基础及前沿技术研究计划项目(11JCYBJC04700,12JCQNJC05500) |
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作者简介: |
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In this present study, different PVDF modified membranes were prepared by non-solvent induced phase separation (NIPS) method. The effects of PVDF solid content, polyethylene glycol (PEG) - 400 solid content on membranes performances were researched. In addition, the performance of different PVDF modified membranes and F60S membranes, saled on the market, were compared and analysed. The results showed that, the membranes aperture and pure water flux decreases gradually with the increase of PVDF solid content, BSA retention rate and mechanical property increased. The aperture of membranes decreased and then increased with PEG-400 solid content increased, BSA retention rate increased and then decreased gradually, the pure water flux increased, and mechanical properties decreased. The aperture and pure water flux of PVDF/PEG membrane were slightly smaller than F60S membrane, BSA retention rate, mechanical properties and blood compatibility of PVDF/PEG membrane were better than F60S membrane. |
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参考文献: |
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[1] 王许云,张林,王新,等.铸膜液溶解温度对制备PVDF微孔膜结构的影响[J].高分子材料科学与工程,2009,25(10):87-90. |
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