本文模拟发酵液中的蛋白质﹑美拉德产物来研究其对聚醚砜超滤膜的污染情况，主要考察污染物浓度及温度、压力等操作条件对膜污染的影响，并分析相应的总阻力﹑各部分膜阻力及其分布情况。结果表明浓度越大，膜阻力上升越快；提高操作温度和压力可一定程度地提高膜通量，但也导致膜总阻力增大，且各部分阻力及其分布情况均发生明显变化；在蛋白质中加入葡萄糖发生美拉德反应后膜阻力明显上升，污染程度大大增加

In this paper, protein and Maillard products in a simulated fermentation broth on membrane fouling of polyethersulfone Ultrafiltration membranes were studied，mainly studied the concentrations and operating temperature and pressure on Membrane fouling. Five parts of membrane resistance and its distribution were analysised. It was found that, membrane flux decreased more quickly at higher concentration, but membrane resistance increased quickly ; rising the operating temperature and pressure could increase the membrane flux , also increase resistances and the various parts of the resistance and its distribution changed significantly. Membrane resistances increased and membrane fouling increased obviously after adding the glucose into the protein and produce the Maillard reaction.

[1]赵平,张月萍,于奕峰,等.膜技术在发酵液后处理过程中的应用[J].膜科学与技术,2002,22(1):54-58.
[2]郑文华,许旭.美拉德反应的研究进展[J].化学进展,2005,17(1):122-127.
[3]王菲菲,曹龙奎.玉米淀粉制取葡萄糖的工艺研究[J].农产品加工,2009,12:70-74.
[4]Kim K.J, Fane A.G, Fell C.J.D, et a1.Fouling mechanisms of membranes during protein ultra-filtration[J]. Journal of Membrane Science,1992,68(1-2):79-91．
[5]Huisman I H, Pradanos P, Hernandez A. The effect of protein-protein and protein-membrane
interactions on membrane fouling in ultra-filtration[J]. Journal of Membrane Science,2000,
179(1):79-90.
[6]Jones K L, O ' Melia C R. Protein and humic acid adsorption onto hydrophilic membrane
surfaces：Effects of pH and ionic strength[J]. Journal of Membrane Science,2000,165(1):
31-46．
[7]Tang C Y, Leckie J O. Membrane independent limiting flux for RO and NF membranes fouled by humic acid[J]. Environmental Science and Technology,2007,41(13):4767-4773．
[8]付莉,李铁刚.简述美拉德反应[J]食品科技,2006(12):9-11.
[9]李书国,陈辉,李雪梅等.大豆蛋白超滤中的膜污染与清洗方法的研究[J].西部粮油科技.2001,26(5):22-25
[10] Zheng X, Ernst M, Huck P.M, et al. Biopolymer fouling in dead-end ultrafiltration of treated domestic wastewater[J].Water Research. 2010,44(18):5212-5221.
[11]张一飞,齐笑飞,乔建援,等.1,3-丙二醇发酵液过滤除菌过程中的膜污染与再生[J].河南化工,2009,26(3):14-16.