采用响应曲面法，对纳滤法深度去除高盐煤制油废水中重金属离子的过程进行了实验设计与分析，结果表明：在C（EDTA）:C（M2+）为1.0:1.1、渗透压为1.89 MPa、pH为 4.1和进料流量为298.9 L/h时，NF90-2540纳滤膜对重金属离子的截留效果最好，重金属离子的截留率可达到97.5%。由三维立体图和等高线图分析可知：使用络合纳滤法截留废水中重金属离子过程中，重金属离子的截留率主要是受纳滤膜的空间位阻作用影响；络合剂投加量与pH的交互影响显著，而其他因素的交互作用不显著。

 Response surface methodology (RSM) was used to study the process of deep removal of heavy metal ions from high-salt coal-based oil-making wastewater by nanofiltration. The fitting results showed that NF90-2540 has the best interception of heavy metal ions and the retention rate can reach 97.5% under the conditions of C（EDTA）:C（M2+）= 1.0:1.1、osmotic pressure= 1.89 MPa、pH= 4.1、feed flow rate= 298.9 L/h. Through analysis of the three-dimensional perspective and contour plots in the response surface methodology, it can be seen that when complexing nanofiltration intercepts heavy metal ions in wastewater, it is mainly affected by the steric hindrance of the nanofiltration membrane. The interaction between complexing agent and pH was significant, indicating that the complexation of heavy metal ions with complexing agents is mainly affected by pH. The interaction of other factors was not significant.

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